| Title | Conception, design, and development of intensified hybrid-bioprocesses |
|---|---|
| ID_Doc | 12977 |
| Authors | Prado-Rubio, OA; Fontalvo, J; Woodley, JM |
| Title | Conception, design, and development of intensified hybrid-bioprocesses |
| Year | 2019 |
| Published | |
| Abstract | The exponential growth in demand for energy, food/feed, and commodities driven by the increasing world population imposes tremendous stress on optimization of technology. The need for process development toward a greener industry and circular economy was the motivation to propose the UN sustainable development goals for 2050. Within this trend, bioprocesses offer the exploitation of renewable resources to be transformed into food, feed, chemicals, materials, or energy promising a long-term sustainable industry. Despite huge interest, many bioprocesses have shown techno-economic constraints and even infeasibility due the trade-off between sustainability performance indexes. Therefore, further research is necessary to developing novel technologies for bioprocesses that can overcome current process constraints. However, this is not a straightforward task due to the particular complexity of bioprocesses such as the variance of raw materials characteristics and availability, lack of process understanding, complex systems interactions, bio systems sensitivity, reliability and reproducibility of experiments (uncertain information), and monitoring difficulties. These challenges imply that methodologies to conceive, design, scale-up, and operate intensified bioprocesses are still under development. This chapter highlights the importance of intensified hybrid bioprocesses and discusses the interdisciplinary approach required to accomplish it. We outline bioprocess hybrid technologies reported in literature and current challenges of bioprocesses intensification at different levels. We present an overview of important ideas addressed within methodologies proposed for designing hybrid bioprocesses. As case studies, hybrid membrane bioreactors for biofuels and organic acids production are used to show how process understanding drives developments in hybrid bioprocesses. Finally, some forthcoming challenges and perspectives are presented for future bioprocess development. |
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