| Title | Anchoring of silver nanoparticles by a zinc-porphyrin covalent organic framework for synergistic photodynamic sterilization |
|---|---|
| ID_Doc | 15350 |
| Authors | Fu, QB; Zhang, TT; An, MZ; Sun, X; Li, YJ; Zhang, BW; Zhang, SK; Waterhouse, GIN; Liu, XN; Li, HS; Ai, SY |
| Title | Anchoring of silver nanoparticles by a zinc-porphyrin covalent organic framework for synergistic photodynamic sterilization |
| Year | 2024 |
| Published | |
| Abstract | Porphyrin-based covalent organic frameworks (Por-COFs) show great promise in photodynamic sterilization and elimination of pathogenic bacteria. In this work, a two-dimensional Por-COF was constructed using 5,10,15,20Tetrakis-(4-aminophenyl)-porphine-Zn(II) (Zn-TAPP) and Dihydroxyterephthalaldehyde (Dha), which was postsynthetically modified with silver nanoparticles (Ag NPs). Ag@ZnPor-COF delivered extraordinary photodynamic inactivation performance against Staphylococcus aureus and Escherichia coli under visible light (99.96 % and 99.75 %, respectively, within 20 min). The localized surface plasmon resonance of the Ag NPs enhanced the absorption of visible light whilst also aiding electron-hole separation, leading to efficient generation of reactive oxygen species (ROS), especially singlet oxygen (1O2). Further, the Ag NPs imparted Ag@ZnPor-COF with photothermal properties, thereby delivering even more effective control of pathogenic bacteria. Density functional theory (DFT) calculations validated the experimental findings, identifying Ag@ZnPor-COF as a potent antibacterial platform. Results encourage the wider use of Por-COFs and plasmonic nanomaterials in the development of antibacterial systems. |
No similar articles found.