Title | Toxicological profile of calcium carbonate nanoparticles for industrial applications |
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ID_Doc | 18106 |
Authors | d'Amora, M; Liendo, F; Deorsola, FA; Bensaid, S; Giordani, S |
Title | Toxicological profile of calcium carbonate nanoparticles for industrial applications |
Year | 2020 |
Published | |
Abstract | Calcium carbonate nanoparticles (CaCO(3)NPs) derived from CO2 are promising materials for different industrial applications. It is imperative to understand their toxicological profile in biological systems as the human and environmental exposures to CaCO(3)NPs increases with growing production. Here, we analyse the cytotoxicity of CaCO(3)NPs synthesized from a CaO slurry on two cell lines, and in vivo on zebrafish (Danio Rerio). Our results demonstrate the CaCO(3)NPs in vitro safety as they do not cause cell death or genotoxicity. Moreover, zebrafish treated with CaCO(3)NPs develop without any abnormalities, confirming the safety and biocompatibility of this nanomaterial. |
https://doi.org/10.1016/j.colsurfb.2020.110947 |
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