Knowledge Agora

Title	Advancements and current challenges in the sustainable downstream processing of bacterial polyhydroxyalkanoates
ID_Doc	29156
Authors	Haque, MA; Priya, A; Hathi, ZJ; Qin, ZH; Mettu, S; Lin, CSK
Title	Advancements and current challenges in the sustainable downstream processing of bacterial polyhydroxyalkanoates
Year	2022
Published
Abstract	Diminishing sources of synthetic plastics and their unsustainable production processes have increased the demand for alternative biodegradable and sustainable polymers. Bacterial biopolymer-producing factories can carry out large-scale production of such alternatives using improved fermentation techniques, such as fed-batch and pulsed feeding of inducers, that can increase bacterial biopolymer accumulation. However, the successive downstream processing (DSP) techniques still pose challenges in making the production process both economically and environmentally sustainable. These challenges are mostly associated with biomass pre-treatment, the use of solvents, and the embedded parameters of the DSP techniques. Conventional halogenated/chlorinated solvents can be substituted with green solvents to yield PHAs of high purity (98%) for high-end applications and to establish a sustainable circular economy. As an economically and environmentally sustainable approach, the use of recycled waste as a substrate and greener extraction solvents for bacterial biopolymer production should be further explored for the efficient replacement of synthetic plastic production.
PDF

Similar Articles

ID	Score	Article
9197		González-Rojo, S; Paniagua-García, AI; Díez-Antolínez, R Advances in Microbial Biotechnology for Sustainable Alternatives to Petroleum-Based Plastics: A Comprehensive Review of Polyhydroxyalkanoate Production(2024)Microorganisms, 12.0, 8
8026		Abbas, MI; Amelia, TSM; Bhubalan, K; Vigneswari, S; Ramakrishna, S; Amirul, AAA Bioprospecting waste for polyhydroxyalkanoates production: embracing low carbon bioeconomy(2024)
20576		Zhou, W; Bergsma, S; Colpa, DI; Euverink, GJW; Krooneman, J Polyhydroxyalkanoates (PHAs) synthesis and degradation by microbes and applications towards a circular economy(2023)
6293		Mannina, G; Presti, D; Montiel-Jarillo, G; Carrera, J; Suárez-Ojeda, ME Recovery of polyhydroxyalkanoates (PHAs) from wastewater: A review(2020)
13152		Ahuja, V; Singh, PK; Mahata, C; Jeon, JM; Kumar, G; Yang, YH; Bhatia, SK A review on microbes mediated resource recovery and bioplastic (polyhydroxyalkanoates) production from wastewater(2024)Microbial Cell Factories, 23, 1
13253		Zytner, P; Kumar, D; Elsayed, A; Mohanty, A; Ramarao, BV; Misra, M A review on polyhydroxyalkanoate (PHA) production through the use of lignocellulosic biomass(2023)Rsc Sustainability, 1, 9
24957		Fernandez-Dacosta, C; Posada, JA; Kleerebezem, R; Cuellar, MC; Ramirez, A Microbial community-based polyhydroxyalkanoates (PHAs) production from wastewater: Techno-economic analysis and ex-ante environmental assessment(2015)
10135		Mozejko-Ciesielska, J; Ray, S; Sankhyan, S Recent Challenges and Trends of Polyhydroxyalkanoate Production by Extremophilic Bacteria Using Renewable Feedstocks(2023)Polymers, 15, 22
12889		Corchado-Lopo, C; Martínez-Avila, O; Marti, E; Llimós, J; Busquets, AM; Kucera, D; Obruca, S; Llenas, L; Ponsá, S Brewer's spent grain as a no-cost substrate for polyhydroxyalkanoates production: Assessment of pretreatment strategies and different bacterial strains(2021)
8254		Andhalkar, VV; Ahorsu, R; de María, PD; Winterburn, J; Medina, F; Constantí, M Valorization of Lignocellulose by Producing Polyhydroxyalkanoates under Circular Bioeconomy Premises: Facts and Challenges(2022)