| Title | Pressurized Extraction as an Opportunity to Recover Antioxidants from Orange Peels: Heat treatment and Nanoemulsion Design for Modulating Oxidative Stress |
|---|---|
| ID_Doc | 29287 |
| Authors | Castro-Vázquez, L; Lozano, MV; Rodríguez-Robledo, V; González-Fuentes, J; Marcos, P; Villaseca, N; Arroyo-Jiménez, MM; Santander-Ortega, MJ |
| Title | Pressurized Extraction as an Opportunity to Recover Antioxidants from Orange Peels: Heat treatment and Nanoemulsion Design for Modulating Oxidative Stress |
| Year | 2021 |
| Published | Molecules, 26.0, 19 |
| Abstract | Orange peel by-products generated in the food industry are an important source of value-added compounds that can be potentially reused. In the current research, the effect of oven-drying (50-70 & DEG;C) and freeze-drying on the bioactive compounds and antioxidant potential from Navelina, Salustriana, and Sanguina peel waste was investigated using pressurized extraction (ASE). Sixty volatile components were identified by ASE-GC-MS. The levels of terpene derivatives (sesquitenenes, alcohols, aldehydes, hydrocarbons, and esters) remained practically unaffected among fresh and freeze-dried orange peels, whereas drying at 70 & DEG;C caused significative decreases in Navelina, Salustriana, and Sanguina peels. Hesperidin and narirutin were the main flavonoids quantified by HPLC-MS. Freeze-dried Sanguina peels showed the highest levels of total-polyphenols (113.3 mg GAE & BULL;g(-1)), total flavonoids (39.0 mg QE & BULL;g(-1)), outstanding values of hesperedin (187.6 mu g & BULL;g(-1)), phenol acids (16.54 mg & BULL;g(-1) DW), and the greatest antioxidant values (DPPH & BULL;, FRAP, and ABTS(& BULL;+) assays) in comparison with oven-dried samples and the other varieties. Nanotechnology approaches allowed the formulation of antioxidant-loaded nanoemulsions, stabilized with lecithin, starting from orange peel extracts. Those provided 70-80% of protection against oxidative UV-radiation, also decreasing the ROS levels into the Caco-2 cells. Overall, pressurized extracts from freeze-drying orange peel can be considered a good source of natural antioxidants that could be exploited in food applications for the development of new products of commercial interest. |
| https://www.mdpi.com/1420-3049/26/19/5928/pdf?version=1633911544 |
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