| Title |
Green process of biomass waste derived fluorescent carbon quantum dots for biological imaging in vitro and in vivo |
| ID_Doc |
13906 |
| Authors |
Ren, HT; Yuan, Y; Labidi, A; Dong, QB; Zhang, K; Lichtfouse, E; Allam, AA; Ajarem, JS; Wang, CY |
| Title |
Green process of biomass waste derived fluorescent carbon quantum dots for biological imaging in vitro and in vivo |
| Year |
2023 |
| Published |
Chinese Chemical Letters, 34, 6 |
| DOI |
10.1016/j.cclet.2022.107998 |
| Abstract |
In the context of the circular economy, the huge amounts of biomass waste should be converted into value-added materials and energy to diminish pollution, atmospheric CO2 levels and costly waste dis-posal. Biological imaging usually uses expensive and toxic chemicals e.g., organic dyes, semiconductor quantum dots, calling for safer, greener, cheaper fluorescent probes for biological imaging in vitro and in vivo . In these regards, carbon quantum dots (CQDs)-based fluorescent probes using biomass waste as a precursor may have much higher potential. Here we transformed the biomass waste of peach leaves into value-added fluorescent CQDs through a low-cost and green one-step hydrothermal process. The obtained CQDs show excitation-dependent photoluminescence properties with a fluorescence lifetime of 5.96 ns and a quantum yield of 7.71% without any passivation. In addition, the CQDs have a fine size of 1.9 nm with good hydrophilicity and high fluorescent stability over pH 4.0-11.0 range. Fluorescence imaging of in vitro cell cultures and in vivo with zebrafish show that CQDs possess ultra-low toxicity and remarkable performance for biological imaging. Even when CQDs present at a concentration as high as 500 mu g/mL, the organism can still maintain more than 90% activity both in vitro and in vivo , and present bright fluorescence. The cheaper, greener, ultra-low toxicity CQDs developed in this work is a potential candidate for biological imaging in vitro and in vivo . (c) 2023 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. |
| Author Keywords |
Carbon quantum dots; Biomass waste; Biological imaging; Bioresource conversion; Green extraction |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Science Citation Index Expanded (SCI-EXPANDED) |
| EID |
WOS:000978106400001 |
| WoS Category |
Chemistry, Multidisciplinary |
| Research Area |
Chemistry |
| PDF |
https://hal.science/hal-04065114/file/RenGreenChineseChemLett2023revised.pdf
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