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Title Green Synthesis of Sucrose Octaacetate and Characterization of Its Physicochemical Properties and Antimicrobial Activity
ID_Doc 14966
Authors Petkova, N; Vassilev, D; Grudeva, R; Tumbarski, Y; Vasileva, I; Koleva, M; Denev, P
Title Green Synthesis of Sucrose Octaacetate and Characterization of Its Physicochemical Properties and Antimicrobial Activity
Year 2017
Published Chemical And Biochemical Engineering Quarterly, 31, 4
DOI 10.15255/CABEQ.2017.1117
Abstract Sucrose octaacetate (octa-O-acetylsucrose) has been synthesized by esterification of sucrose with acetic anhydride using ultrasound-assisted irradiation. This sucrose ester is a white, water-insoluble substance with a bitter taste. The FT-IR and NMR spectra confirmed acetylation and revealed the hydrophobic incorporation in sucrose molecule. Furthermore, the foamability, foam stability, emulsification and antimicrobial properties of octa-O-acetylsucrose were evaluated. Foams and 50 % (oil/water) model emulsions were prepared with 2 % (w/w) octa-O-acetylsucrose. The obtained results demonstrate the formation of emulsions and foams with high stability (50-70 %). The antimicrobial activity of octa-O-acetylsucrose was evaluated against seventeen microorganisms (Gram-positive and Gram-negative bacteria, yeasts, and fungi). Octa-O-acetylsucrose -inhibited the growth of fungi Penicillium sp., Rhizopus sp. and Fusarium moniliforme at 5 mg cm(-3), and yeasts Candida albicans at 1 mg cm(-3). Inhibition against Gram-positive and Gram-negative bacteria was not observed. The obtained results demonstrate the potential applications of octa-O-acetylsucrose as a foaming agent, oil-in-water emulsion stabilizer, and antifungal substance in pharmaceutical and cosmetic preparations.
Author Keywords octa-O-acetylsucrose; ultrasound-assisted synthesis; foam; antimicrobial properties
Index Keywords Index Keywords
Document Type Other
Open Access Open Access
Source Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S)
EID WOS:000423238500004
WoS Category Biotechnology & Applied Microbiology; Engineering, Chemical
Research Area Biotechnology & Applied Microbiology; Engineering
PDF https://doi.org/10.15255/cabeq.2017.1117
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