Title |
Green Synthesis of Sucrose Octaacetate and Characterization of Its Physicochemical Properties and Antimicrobial Activity |
ID_Doc |
14966 |
Authors |
Petkova, N; Vassilev, D; Grudeva, R; Tumbarski, Y; Vasileva, I; Koleva, M; Denev, P |
Title |
Green Synthesis of Sucrose Octaacetate and Characterization of Its Physicochemical Properties and Antimicrobial Activity |
Year |
2017 |
Published |
Chemical And Biochemical Engineering Quarterly, 31, 4 |
DOI |
10.15255/CABEQ.2017.1117 |
Abstract |
Sucrose octaacetate (octa-O-acetylsucrose) has been synthesized by esterification of sucrose with acetic anhydride using ultrasound-assisted irradiation. This sucrose ester is a white, water-insoluble substance with a bitter taste. The FT-IR and NMR spectra confirmed acetylation and revealed the hydrophobic incorporation in sucrose molecule. Furthermore, the foamability, foam stability, emulsification and antimicrobial properties of octa-O-acetylsucrose were evaluated. Foams and 50 % (oil/water) model emulsions were prepared with 2 % (w/w) octa-O-acetylsucrose. The obtained results demonstrate the formation of emulsions and foams with high stability (50-70 %). The antimicrobial activity of octa-O-acetylsucrose was evaluated against seventeen microorganisms (Gram-positive and Gram-negative bacteria, yeasts, and fungi). Octa-O-acetylsucrose -inhibited the growth of fungi Penicillium sp., Rhizopus sp. and Fusarium moniliforme at 5 mg cm(-3), and yeasts Candida albicans at 1 mg cm(-3). Inhibition against Gram-positive and Gram-negative bacteria was not observed. The obtained results demonstrate the potential applications of octa-O-acetylsucrose as a foaming agent, oil-in-water emulsion stabilizer, and antifungal substance in pharmaceutical and cosmetic preparations. |
Author Keywords |
octa-O-acetylsucrose; ultrasound-assisted synthesis; foam; antimicrobial properties |
Index Keywords |
Index Keywords |
Document Type |
Other |
Open Access |
Open Access |
Source |
Science Citation Index Expanded (SCI-EXPANDED); Conference Proceedings Citation Index - Science (CPCI-S) |
EID |
WOS:000423238500004 |
WoS Category |
Biotechnology & Applied Microbiology; Engineering, Chemical |
Research Area |
Biotechnology & Applied Microbiology; Engineering |
PDF |
https://doi.org/10.15255/cabeq.2017.1117
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