| Title |
Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
| ID_Doc |
15601 |
| Authors |
Cardeira, M; Bernardo, A; Leonardo, IC; Gaspar, FB; Marques, M; Melgosa, R; Paiva, A; Simoes, P; Fernández, N; Serra, AT |
| Title |
Cosmeceutical Potential of Extracts Derived from Fishery Industry Residues: Sardine Wastes and Codfish Frames |
| Year |
2022 |
| Published |
Antioxidants, 11, 10 |
| DOI |
10.3390/antiox11101925 |
| Abstract |
The fishery industry generates large amounts of waste (20-75% (w/w) of the total caught fish weight). The recovery of bioactive compounds from residues and their incorporation in cosmetics represents a promising market opportunity and may contribute to a sustainable valorisation of the sector. In this work, protein-rich extracts obtained by high-pressure technologies (supercritical CO2 and subcritical water) from sardine (Sardina pilchardus) waste and codfish (Gadus morhua) frames were characterized regarding their cosmeceutical potential. Antioxidant, anti-inflammatory and antibacterial activities were evaluated through chemical (ORAC assay), enzymatic (inhibition of elastase and tyrosinase), antimicrobial susceptibility (Klebsiella pneumoniae, Staphylococcus aureus and Cutibacterium acnes) and cell-based (in keratinocytes-HaCaT) assays. Sardine extracts presented the highest antibacterial activity, and the extract obtained using higher extraction temperatures (250 degrees C) and without the defatting step demonstrated the lowest minimum inhibitory concentration (MIC) values (1.17; 4.6; 0.59 mg/mL for K. pneumoniae, S. aureus and C. acnes, respectively). Codfish samples extracted at lower temperatures (90 degrees C) were the most effective anti-inflammatory agents (a concentration of 0.75 mg/mL reduced IL-8 and IL-6 levels by 58% and 47%, respectively, relative to the positive control). Threonine, valine, leucine, arginine and total protein content in the extracts were highlighted to present a high correlation with the reported bioactivities (R-2 >= 0.7). These results support the potential application of extracts obtained from fishery industry wastes in cosmeceutical products with bioactive activities. |
| Author Keywords |
fish waste streams valorisation; antioxidant activity; anti-inflammatory activity; antimicrobial activity; anti-ageing; anti-hyperpigmentation; cosmeceuticals |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Science Citation Index Expanded (SCI-EXPANDED) |
| EID |
WOS:000872027400001 |
| WoS Category |
Biochemistry & Molecular Biology; Chemistry, Medicinal; Food Science & Technology |
| Research Area |
Biochemistry & Molecular Biology; Pharmacology & Pharmacy; Food Science & Technology |
| PDF |
https://www.mdpi.com/2076-3921/11/10/1925/pdf?version=1664435652
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