| Title |
Synthesis of bioinspired based hydrogel composite from hyaluronic acid/polyacrylic acid and lignin as an adhesive for medical technology |
| ID_Doc |
17411 |
| Authors |
Glingasorn, B; Yongsapanan, N; Pangon, A; Lin, CC; Ummartyotin, S |
| Title |
Synthesis of bioinspired based hydrogel composite from hyaluronic acid/polyacrylic acid and lignin as an adhesive for medical technology |
| Year |
2024 |
| Published |
Emergent Materials, 7, 1 |
| DOI |
10.1007/s42247-023-00592-y |
| Abstract |
Owing to the concern over degradation in medical technology, bio-based composites have been extensively developed. Recently, bioinspired hydrogel composites as an adhesive have been prepared. The hyaluronic acid (HA)/polyacrylic acid (PAA)/lignin hydrogel composite is successfully prepared by polymerization of acrylic acid (AA) in the presence of hyaluronic acid and lignin using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride as a coupling agent. The gel is brown in color when lignin is integrated. The broad OH absorption band presented in the FTIR spectra indicated that the hydrogel with the presence of lignin formed a thorough hydrogen bond network. The morphology of a hydrogel is typically presented as an interconnected structure due to sublimation of water. With increasing lignin content, the pore size increases. The hydrogel is thermally stable up to 200 oC and no weight loss is observed. The gel fraction is estimated to be 60-80%. The swelling behavior is very rapid within the initial stage (5 h), suggesting that the release mechanism should be investigated. The compressive strength is reported to be 24-28 KPa. It is evident that the hyaluronic acid/polyacrylic acid/lignin hydrogels exhibit excellent characteristic to be an adhesive, as demonstrated by the adhesion of the hydrogel on a plastic surface. The bioinspired hydrogel composite will significantly fulfill the great promise of eco-friendly usage with the additional features of biocompatibility and biodegradability. |
| Author Keywords |
Lignin; Adhesive; Composite; Polyacrylic acid; Hyaluronic acid; Hydrogel |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Emerging Sources Citation Index (ESCI) |
| EID |
WOS:001108139700002 |
| WoS Category |
Materials Science, Multidisciplinary |
| Research Area |
Materials Science |
| PDF |
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