| Title |
Microbial cell factories for the production of three-carbon backbone organic acids from agro-industrial wastes |
| ID_Doc |
27683 |
| Authors |
Son, J; Baritugo, KA; Lim, SH; Lim, HJ; Jeong, S; Lee, JY; Choi, JI; Joo, JC; Na, JG; Park, SJ |
| Title |
Microbial cell factories for the production of three-carbon backbone organic acids from agro-industrial wastes |
| Year |
2022 |
| Published |
|
| DOI |
10.1016/j.biortech.2022.126797 |
| Abstract |
At present, mass production of basic and valuable commodities is dependent on linear petroleum-based industries, which ultimately makes the depletion of finite natural reserves and accumulation of non-biodegradable and hazardous wastes. Therefore, an ecofriendly and sustainable solution should be established for a circular economy where infinite resources, such as agro-industrial wastes, are fully utilized as substrates in the production of target value-added chemicals. Hereby, recent advances in metabolic engineering strategies and techniques used in the development of microbial cell factories for enhanced production of three-carbon platform chemicals such as lactic acid, propionic acid, and 3-hydroxypropionic acid are discussed. Further developments and future perspectives in the production of these organic acids from agro-industrial wastes from the dairy, sugar, and biodiesel industries are also highlighted to demonstrate the importance of waste-based biorefineries for organic acid production. |
| Author Keywords |
Agro-industrial wastes; Three-carbon platform chemicals; Microbial cell factory; Metabolic engineering; Circular economy |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Science Citation Index Expanded (SCI-EXPANDED) |
| EID |
WOS:000783018900006 |
| WoS Category |
Agricultural Engineering; Biotechnology & Applied Microbiology; Energy & Fuels |
| Research Area |
Agriculture; Biotechnology & Applied Microbiology; Energy & Fuels |
| PDF |
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