| Title |
From tetroses to methionine hydroxy analogues through Sn (IV) Lewis acid catalysis using methanethiol as sulphur feedstock |
| ID_Doc |
29063 |
| Authors |
Calderon-Ardila, S; Rammal, F; Peeters, E; Van Waeyenberg, J; Peruch, O; Morvan, D; Belliere-Baca, V; Dusselier, M; Sels, BF |
| Title |
From tetroses to methionine hydroxy analogues through Sn (IV) Lewis acid catalysis using methanethiol as sulphur feedstock |
| Year |
2023 |
| Published |
|
| DOI |
10.1016/j.cattod.2023.114137 |
| Abstract |
Methionine hydroxy analogues (MHAs) form part of a million tonne scale commodity market of compounds useful in livestock nutrition. The chemocatalytic synthesis of MHAs from carbohydrates is an important albeit understudied transformation en route to a sustainable and circular economy. Here we report our first results for the conversion of tetroses to MHAs in the presence of methanethiol (MeSH) and SnCl4 center dot 5H(2)O. Our study allowed to corroborate the major reaction pathways involved in this Lewis acid-catalysed transformation. It was also found that the ratio between MeSH and MeOH, the pressure of inert gas, and the water content strongly affect the reaction performance. When these parameters were combined the yield and selectivity towards MHAs increased to the highest reported value of 38 % in one hour reactions at 413 K. Our findings have the potential to unlock the sustainable synthesis of MHAs from renewable feedstock such as tetroses and other carbohydrates. |
| Author Keywords |
Alpha-hydroxy esters; Biomass; Homogeneous catalysis; Lewis acids; Methionine hydroxy analogue; Tetroses |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Science Citation Index Expanded (SCI-EXPANDED) |
| EID |
WOS:000976650100001 |
| WoS Category |
Chemistry, Applied; Chemistry, Physical; Engineering, Chemical |
| Research Area |
Chemistry; Engineering |
| PDF |
https://lirias.kuleuven.be/bitstream/20.500.12942/720382/2/1-s2.0-S092058612300161X-main.pdf
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