| Title |
From Kiwi Peels' "End-of-Life" to Gold Nanoparticles: the Upcycling of a Waste |
| ID_Doc |
6689 |
| Authors |
Gubitosa, J; Rizzi, V; Maggi, F; Laurenzana, A; Caprioli, G; Anceschi, C; Mustafa, AM; Fini, P; Cosma, P |
| Title |
From Kiwi Peels' "End-of-Life" to Gold Nanoparticles: the Upcycling of a Waste |
| Year |
2023 |
| Published |
Bionanoscience, 13, 4 |
| DOI |
10.1007/s12668-023-01179-x |
| Abstract |
Following a green approach, kiwi peels (a waste) were washed in hot water to obtain a water-based polyphenolic extract (KPWW) used to reduce Au3+ (coming from a HAuCl4 water-based solution) for forming gold nanoparticles (AuNPs). Indeed, KPWW, as shown after performing high-performance liquid chromatography-mass spectrometry (HPLC/MS-MS) analysis, is mainly composed by different polyphenols acting as reductant agents, accomplishing a red-ox reaction and decorating the AuNPs-KPWW surface. Spectroscopic and morphologic techniques were used in synergy for investigating the AuNPs-KPWW main features. Polyhedral-shaped plasmonic nanoparticles with a mean size of 30 & PLUSMN;10 nm and a negative charge of -40 mV were thus obtained. The AuNPs' stability was assessed under different working conditions, investigating the role of ionic strength, pH, and temperature. The photostability was also assessed by irradiating AuNPs-KPWW with a solar simulator lamp. Both temperature and solar light did not perturb AuNPs-KPWW. Thanks to the presence of polyphenols, the antioxidant and skin-lightening properties were positively demonstrated. Moreover, the protective role of AuNPs in scavenging H2O2 and & BULL;OH was also investigated by inhibiting the oxidation of a biomolecule. The sunscreen ability of AuNPs-KPWW was also estimated, and the theoretical calculation of the sun protection factor (SPF) was determined. Finally, the AuNPs-KPWW biocompatibility was tested on endothelial colony-forming cells and normal dermal fibroblasts as human cell lines, revealing that AuNPs-KPWW did not affect cell viability and did not alter cell morphology, demonstrating their safety and their potential application in nanomedicine. |
| Author Keywords |
Gold nanoparticles; Kiwi peel extract; Polyphenols; Green chemistry; Circular economy; Waste management; Biomedicine; Cosmetics |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Emerging Sources Citation Index (ESCI) |
| EID |
WOS:001052032900002 |
| WoS Category |
Materials Science, Biomaterials |
| Research Area |
Materials Science |
| PDF |
https://link.springer.com/content/pdf/10.1007/s12668-023-01179-x.pdf
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