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Title aPDI meets PPE: photochemical decontamination in healthcare using methylene blue-where are we now, where will we go?
ID_Doc 7452
Authors Ludwig-Begall, LF; Heyne, B
Title aPDI meets PPE: photochemical decontamination in healthcare using methylene blue-where are we now, where will we go?
Year 2024
Published Photochemical & Photobiological Sciences, 23, 2
DOI 10.1007/s43630-023-00514-1
Abstract Personal protective equipment (PPE) reuse, first recommended in the context of the SARS-CoV-2 pandemic, can mitigate shortages in crisis situations and can greatly reduce the environmental impact of typically single-use PPE. Prior to safe reuse, PPE must be sanitized and contaminating pathogens-in current circumstances viruses in particular-must be inactivated. However, many established decontamination procedures are not equitable and remain unavailable in low-resource settings. In mid-2020, an interdisciplinary consortium of researchers first studied the potential of implementing cheap and easy-to-use antimicrobial photodynamic inactivation (aPDI) using methylene blue as photosensitizer to decontaminate face masks and filtering facepiece respirators. In this perspective piece, we describe the development of this novel method, discuss recent advances, and offer insights into how equitable PPE decontamination via methylene blue-based aPDI may be integrated into circular economy policies in the healthcare sector.
Author Keywords Personal protective equipment; Antimicrobial photodynamic inactivation; SARS-CoV-2; Methylene blue
Index Keywords Index Keywords
Document Type Other
Open Access Open Access
Source Science Citation Index Expanded (SCI-EXPANDED)
EID WOS:001132720800001
WoS Category Biochemistry & Molecular Biology; Biophysics; Chemistry, Physical
Research Area Biochemistry & Molecular Biology; Biophysics; Chemistry
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