| Title |
From Microbial Succinic Acid Production to Polybutylene Bio-Succinate Synthesis |
| ID_Doc |
17234 |
| Authors |
Tenhaef, N; Hermann, A; Müeller, MF; Göertz, J; Marienhagen, J; Oldiges, M; Wiechert, W; Bott, M; Jupke, A; Hartmann, L; Herres-Pawlis, S; Noack, S |
| Title |
From Microbial Succinic Acid Production to Polybutylene Bio-Succinate Synthesis |
| Year |
2023 |
| Published |
Chemie Ingenieur Technik, 95, 4 |
| DOI |
10.1002/cite.202200163 |
| Abstract |
A simplified and scalable one-pot process for the anaerobic production of succinic acid using a metabolically engineered Corynebacterium glutamicum strain is demonstrated. With targeted bioprocess optimization, succinic acid titer of 78 g L-1 and yield of 1.41 mol(SA)mol(GLC)(-1) were achieved. Succinic acid was recovered from the neutral fermentation broth by electrochemically induced crystallization and applied for polybutylene bio-succinate synthesis using a biocompatible zinc catalyst. Except for a slight color change, the final biopolymer was comparable to the polymer from commercial precursors. |
| Author Keywords |
Anaerobic production; Corynebacterium glutamicum; Electrochemically induced crystallization; Polybutylene succinate; Succinic acid |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Science Citation Index Expanded (SCI-EXPANDED) |
| EID |
WOS:000941586600001 |
| WoS Category |
Engineering, Chemical |
| Research Area |
Engineering |
| PDF |
https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cite.202200163
|