| Title |
Consolidated microbial production of four-, five-, and six-carbon organic acids from crop residues: Current status and perspectives |
| ID_Doc |
7491 |
| Authors |
Son, J; Joo, JC; Baritugo, KA; Jeong, S; Lee, JY; Lim, HJ; Lim, SH; Yoo, JI; Park, SJ |
| Title |
Consolidated microbial production of four-, five-, and six-carbon organic acids from crop residues: Current status and perspectives |
| Year |
2022 |
| Published |
|
| DOI |
10.1016/j.biortech.2022.127001 |
| Abstract |
The production of platform organic acids has been heavily dependent on petroleum-based industries. However, petrochemical-based industries that cannot guarantee a virtuous cycle of carbons released during various processes are now facing obsolescence because of the depletion of finite fossil fuel reserves and associated environmental pollutions. Thus, the transition into a circular economy in terms of the carbon footprint has been evaluated with the development of efficient microbial cell factories using renewable feedstocks. Herein, the recent progress on bio-based production of organic acids with four-, five-, and six-carbon backbones, including butyric acid and 3-hydroxybutyric acid (C4), 5-aminolevulinic acid and citramalic acid (C5), and hexanoic acid (C6), is discussed. Then, the current research on the production of C4-C6 organic acids is illustrated to suggest future directions for developing crop-residue based consolidated bioprocessing of C4-C6 organic acids using host strains with tailor-made capabilities. |
| Author Keywords |
Organic acids; Microbial cell factory; Crop residues; Consolidated bioprocessing; Metabolic engineering |
| Index Keywords |
Index Keywords |
| Document Type |
Other |
| Open Access |
Open Access |
| Source |
Science Citation Index Expanded (SCI-EXPANDED) |
| EID |
WOS:000793399500003 |
| WoS Category |
Agricultural Engineering; Biotechnology & Applied Microbiology; Energy & Fuels |
| Research Area |
Agriculture; Biotechnology & Applied Microbiology; Energy & Fuels |
| PDF |
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